The nonsuppurative meningo-polioencephalomyelitis

Investigations were made on 24 dead piglets after the specific neurological signs for Teschen disease, the porcine enterovirus tipe 1 being isolated from some of patients in the specialized laboratories. Pathological matter inoculated in embrionated eggs have produced the death of the embrios with nespecific haemorrhagic diathesis and generalized oedema The necropsical lesions were practically absent. The histological lesions were widely distributed, more severe and extensive in the cerebelum, the brain stem and the ventral horns of the spinal cord, and have cosisting in the nonsuppurative meningo-polioencephalomyelitis. Cerebellar hyperplastic menigitis of lymphoplasmocytic type and cerebellitis with diffuse gliosis, satelitosis and neuronophagia of the Purkinje cells, glial nodules and perivascular cuffings in the grey and white matter were associated with congestion, microhaemorrhages, microthrombosis, oedema and malacia. Similar lesions were present in the cerebral cortex and brain stem. Motor neurons from central nuclei of the ventral horns were the most affected and the inflamatory infiltrates were ample, but the spinal meningitis was discrete.
Keywords:    porcine, enterovirus, meningitis,  polioencephalomylitis.